Aniracetam Package Insert

ALSO KNOWN AS N-anisoyl-2-pyrrolidinone, 1-(4-methoxybenzoyl)pyrrolidin-2-one, Aniracetamum, Aniracétam, Ro 135057
TRADE NAMES Ampamet, Aniracetam-Sanhome, Memodrin, Draganon, Sarpul, Referan, Pergamid, Bi Si Ling, Bo Bang Lin, San Le Xi, Shuntan, Yi Ling Shu
CATEGORY Nootropic, Racetam, Ampakine
TYPE Nootropic Agent, Central Stimulant, Anxiolytic Agent, Antidepressive Agents
MEDICAL USES
  • Senile Dementia of the Alzheimer type
  • Cognitive Impairment
  • Memory Disorders linked to Cerebrovascular Disease
  • Attention Disturbances of Degenerative Origin
  • Anxiety/Depression after Cerebral Infarction (Stroke)
  • Epilepsy
NON-MEDICAL USES
  • Nootropic
  • Cognitive Enhancement
  • Creativity
  • Mood-Boosting
  • Focus & Motivation
  • Social Anxiety
  • Studying & Academic Performance
MECHANISM OF ACTION
  • Facilitates cholinergic neurotransmission
  • Positive modulator of metabotropic and AMPA ionotropic glutamate receptors
  • Metabolites also exhibit positive effects on memory
  • Increases release of noradrenaline
  • Stimulation of GABA, Serotonin & Dopamine receptors
DOSAGE 750 mg or 1500 mg per day, split into 1 – 2 administrations
STACKED WITH Piracetam, Pramiracetam, Oxiracetam, Phenylpiracetam, Noopept, Choline, Alpha GPC, Citicoline, Centrophenoxine, DMAE, Phosphatidylcholine, Adderall, Modafinil (Provigil), Phenibut
ATC CODE N06BX11 (WHO): N06 Psychoanaleptics > NO6B Psychostimulants, agents used for adhd and nootropics > NO6BX Other psychostimulants and nootropics
CAS REGISTRY NUMBER 0072432-10-1
CHEMICAL FORMULA C12-H13-N-O3
MOLECULAR WEIGHT 219.24 g/mol
ADMINISTRATION Oral, Intravenous
ABSOPRTION Rapidly and completely absorbed from the gastrointestinal tract
ABSOLUTE BIOAVAILABILITY 0.02% due to extensive biodegradation
METABOLITES
  • N-anisoyl-gamma-aminobutyric acid (N-anisoyl-GABA)
  • 2-pyrrolidinone
  • Succinimide
  • Anisic acid
EXCRETION
  • Urine (84%)
  • Feces (2%)
  • Respiration
BIOLOGICAL HALF-LIFE 1 – 2.5 hours